TESK1 Antibody

ProSci
Product Code: PSI-58-727
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-727-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from 293 cell line, using TESK1 Antibody at 1:1000.
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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis of lysate from 293 cell line, using TESK1 Antibody at 1:1000.
Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Dual specificity testis-specific protein kinase 1, Testicular protein kinase 1, TESK1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis.
Background References:
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Johne, C., et al. Mol. Biol. Cell 19(4):1391-1403(2008)
  • LaLonde, D.P., et al. J. Biol. Chem. 280(22):21680-21688(2005)
  • Leeksma, O.C., et al. Eur. J. Biochem. 269(10):2546-2556(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This TESK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the Central region of human TESK1.
NCBI Gene ID #:
7016
NCBI Official Name:
Dual specificity testis-specific protein kinase 1
NCBI Official Symbol:
TESK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q15569
Protein GI Number:
209572684
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q15569
User NOte:
Optimal dilutions for each application to be determined by the researcher.