PLEKHA1 Antibody
| Code | Size | Price |
|---|
| PSI-59-729-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Pleckstrin homology domain-containing family A member 1, PH domain-containing family A member 1, Tandem PH domain-containing protein 1, TAPP-1, PLEKHA1, TAPP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a pleckstrin homology domain-containing
adapter protein. The encoded protein is localized to the plasma
membrane where it specifically binds phosphatidylinositol
3,4-bisphosphate. This protein may be involved in the formation of
signaling complexes in the plasma membrane. Polymorphisms in this
gene are associated with age-related macular degeneration.
Alternate splicing results in multiple transcript variants. A
pseudogene of this gene is found on chromosome 5.
Background References:
- Deangelis, M.M., et al. Ophthalmology 115(7):1209-1215(2008)
- Manna, D., et al. J. Biol. Chem. 282(44):32093-32105(2007)
- Kanda, A., et al. Proc. Natl. Acad. Sci. U.S.A. 104(41):16227-16232(2007)
- Leveziel, N., et al. Mol. Vis. 13, 2153-2159 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PLEKHA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the Central region of human PLEKHA1.
NCBI Gene ID #:
59338
NCBI Official Name:
Pleckstrin homology domain-containing family A member 1
NCBI Official Symbol:
PLEKHA1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q9HB21
Protein GI Number:
48474647
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9HB21
User NOte:
Optimal dilutions for each application to be determined by the researcher.