GRB7 Antibody
| Code | Size | Price |
|---|
| PSI-63-960-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Growth factor receptor-bound protein 7, B47, Epidermal growth factor receptor GRB-7, GRB7 adapter protein, GRB7
Application Note:
For WB starting dilution is: 1:1000
Background:
GRB7 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK).
Background References:
- Depetris, R.S., et al. Nat. Struct. Mol. Biol. 16(8):833-839(2009)
- Chu, P.Y., et al. J. Biol. Chem. 284(30):20215-20226(2009)
- Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)
- Bai, T., et al. Carcinogenesis 29(3):473-479(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GRB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-318 amino acids from the Central region of human GRB7.
NCBI Gene ID #:
2886
NCBI Official Name:
Growth factor receptor-bound protein 7
NCBI Official Symbol:
GRB7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
Q14451
Protein GI Number:
116242503
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q14451
User NOte:
Optimal dilutions for each application to be determined by the researcher.