KRT6A Antibody
| Code | Size | Price |
|---|
| PSI-58-847-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Cytokeratin-6D, CK-6D, Keratin-6A, K6A, Type-II keratin Kb6, Hom s 5, KRT6A, K6A, KRT6D
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
keratin gene family. The type II cytokeratins consist of basic or
neutral proteins which are arranged in pairs of heterotypic keratin
chains coexpressed during differentiation of simple and stratified
epithelial tissues. As many as six of this type II cytokeratin
(KRT6) have been identified; the multiplicity of the genes is
attributed to successive gene duplication events. The genes are
expressed with family members KRT16 and/or KRT17 in the filiform
papillae of the tongue, the stratified epithelial lining of oral
mucosa and esophagus, the outer root sheath of hair follicles, and
the glandular epithelia. This KRT6 gene in particular encodes the
most abundant isoform. Mutations in these genes have been
associated with pachyonychia congenita. The type II cytokeratins
are clustered in a region of chromosome 12q12-q13. [provided by
RefSeq].
Background References:
- Dereure, O. Ann Dermatol Venereol 137(5):423-424(2010)
- Trost, A., et al. Mech. Ageing Dev. 131(5):346-353(2010)
- Yang, L., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(1):66-68(2010)
- Millar, E.K., et al. J. Clin. Oncol. 27(28):4701-4708(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KRT6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human KRT6A.
NCBI Gene ID #:
3853
NCBI Official Name:
Keratin, type II cytoskeletal 6A
NCBI Official Symbol:
KRT6A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
P02538
Protein GI Number:
1346344
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P02538
User NOte:
Optimal dilutions for each application to be determined by the researcher.