HEMGN Antibody
| Code | Size | Price |
|---|
| PSI-56-873-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Hemogen, Erythroid differentiation-associated gene protein, EDAG-1, Hemopoietic gene protein, Negative differentiation regulator protein, HEMGN, EDAG, NDR
Application Note:
For WB starting dilution is: 1:1000
Background:
HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
Background References:
- Ding, Y.L., et al. J. Cell. Biochem. 110(4):866-874(2010)
- Moreno, L.M., et al. Hum. Mol. Genet. 18(24):4879-4896(2009)
- Lowe, J.K., et al. PLoS Genet.(2), E1000365 (2009) :
- Li, C.Y., et al. Biochim. Biophys. Acta 1779(10):606-615(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HEMGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 420-449 amino acids from the C-terminal region of human HEMGN.
NCBI Gene ID #:
55363
NCBI Official Name:
Hemogen
NCBI Official Symbol:
HEMGN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q9BXL5
Protein GI Number:
74752432
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9BXL5
User NOte:
Optimal dilutions for each application to be determined by the researcher.