NOXO1 Antibody

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ProSci
Product Code: PSI-59-241
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-241-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

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Further Information

Additional Names:
NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX, SH3PXD5
Application Note:
For WB starting dilution is: 1:1000
Background:
NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). NOX organizers, such as NOXO1, target NOX activators (see NOXA1; MIM 611255) to NOX and also target NOX to different subcellular compartments (Opitz et al., 2007 [PubMed 17189823]).
Background References:
  • Dutta, S., et al. PLoS ONE(5), E10478 (2010) :
  • Opitz, N., et al. Free Radic. Biol. Med. 42(2):175-179(2007)
  • Yamamoto, A., et al. Biochem. Biophys. Res. Commun. 352(2):560-565(2007)
  • Takeya, R., et al. FEBS J. 273(16):3663-3677(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NOXO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human NOXO1.
NCBI Gene ID #:
124056
NCBI Official Name:
NADPH oxidase organizer 1
NCBI Official Symbol:
NOXO1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
Q8NFA2
Protein GI Number:
74751269
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8NFA2
User NOte:
Optimal dilutions for each application to be determined by the researcher.