CYTH1 Antibody
| Code | Size | Price |
|---|
| PSI-57-556-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the PSCD
family. Members of this family have identical structural
organization that consists of an N-terminal coiled-coil motif, a
central Sec7 domain, and a C-terminal pleckstrin homology (PH)
domain. The coiled-coil motif is involved in homodimerization, the
Sec7 domain contains guanine-nucleotide exchange protein (GEP)
activity, and the PH domain interacts with phospholipids and is
responsible for association of PSCDs with membranes. Members of
this family appear to mediate the regulation of protein sorting and
membrane trafficking. This gene is highly expressed in natural
killer and peripheral T cells, and regulates the adhesiveness of
integrins at the plasma membrane of lymphocytes. The encoded
protein is 83% homologous to that of CYTH2.
Background References:
- El Azreq, M.A., et al. J. Immunol. 184(2):637-649(2010)
- Quast, T., et al. Blood 113(23):5801-5810(2009)
- Sendide, K., et al. J. Immunol. 174(7):4210-4219(2005)
- Boehm, T., et al. EMBO J. 22(5):1014-1024(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CYTH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human CYTH1.
NCBI Gene ID #:
9267
NCBI Official Name:
Cytohesin-1
NCBI Official Symbol:
CYTH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q15438
Protein GI Number:
2498175
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q15438
User NOte:
Optimal dilutions for each application to be determined by the researcher.