AP4B1 Antibody

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ProSci
Product Code: PSI-59-083
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-083-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).

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Further Information

Additional Names:
AP-4 complex subunit beta-1, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta-1, Beta subunit of AP-4, Beta4-adaptin, AP4B1
Application Note:
For WB starting dilution is: 1:1000
Background:
The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243).
Background References:
  • Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
  • Cayrol, C., et al. Biochem. Biophys. Res. Commun. 298(5):720-730(2002)
  • Takatsu, H., et al. Biochem. Biophys. Res. Commun. 284(4):1083-1089(2001)
  • Hirst, J., et al. Mol. Biol. Cell 10(8):2787-2802(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This AP4B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the Central region of human AP4B1.
NCBI Gene ID #:
10717
NCBI Official Name:
AP-4 complex subunit beta-1
NCBI Official Symbol:
AP4B1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
Q9Y6B7
Protein GI Number:
126302520
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y6B7
User NOte:
Optimal dilutions for each application to be determined by the researcher.