SSR4 Antibody
| Code | Size | Price |
|---|
| PSI-58-470-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Translocon-associated protein subunit delta, TRAP-delta, Signal sequence receptor subunit delta, SSR-delta, SSR4, TRAPD
Application Note:
For WB starting dilution is: 1:1000
Background:
SSR4, also called TRAPD, is assumed to be involved in
protein secretion. It is located in the Xq28 region, arranged in a
compact head-to-head manner with the IDH3G gene. These two genes
are driven by a bidirectional promoter located between them, and
encode proteins involved in unrelated biochemical pathways located
in different compartments of the cell. The nontranscribed
intergenic region represents only 133 bp and is embedded in a CpG
island. The CpG island functions as a bidirectional promoter to
initiate the transcription of both functionally unrelated genes
with distinct expression patterns. SSR4 consists of six exons and
is approximately 70 kb telomeric to the ALD gene. Although
alternative splicing of exon 5 has not been detected in human SSR4,
transcript variants missing the region homologous to human exon 5
have been detected in both Xenopus laevis and Mus musculus.
Background References:
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Wang, Z., et al. Melanoma Res. 14(2):107-114(2004)
- Miyazaki, K., et al. J. Biol. Chem. 279(12):11327-11335(2004)
- Wang, L., et al. FEBS Lett. 457(3):316-322(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SSR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human SSR4.
NCBI Gene ID #:
6748
NCBI Official Name:
Translocon-associated protein subunit delta
NCBI Official Symbol:
SSR4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
P51571
Protein GI Number:
1711550
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P51571
User NOte:
Optimal dilutions for each application to be determined by the researcher.