RASAL2 Antibody

ProSci
Product Code: PSI-56-781
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-781-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Ras GTPase-activating protein nGAP, RAS protein activator-like 2, RASAL2, NGAP
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Background References:
  • Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)
  • Shibui, T., et al. Biotechnol. Lett. 30(12):2037-2043(2008)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Noto, S., et al. FEBS Lett. 441(1):127-131(1998)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RASAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 675-703 amino acids from the Central region of human RASAL2.
NCBI Gene ID #:
9462
NCBI Official Name:
Ras GTPase-activating protein nGAP
NCBI Official Symbol:
RASAL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
129 kDa
Protein Accession #:
Q9UJF2
Protein GI Number:
13959419
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9UJF2
User NOte:
Optimal dilutions for each application to be determined by the researcher.