BRAP Antibody

ProSci
Product Code: PSI-60-651
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-651-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in 293 cell line lysates (35ug/lane).

Western blot analysis in 293 cell line lysates (35ug/lane).

Further Information

Additional Names:
BRCA1-associated protein, 632-, BRAP2, Impedes mitogenic signal propagation, IMP, RING finger protein 52, Renal carcinoma antigen NY-REN-63, BRAP (HGNC:1099), RNF52
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. It is a cytoplasmic protein which may regulate nuclear targeting by retaining proteins with a nuclear localization signal in the cytoplasm.
Background References:
  • Fulcher, A.J., et al. FASEB J. 24(5):1454-1466(2010)
  • Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
  • Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)
  • Hinohara, K., et al. J. Hum. Genet. 54(11):642-646(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BRAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human BRAP.
NCBI Gene ID #:
8315
NCBI Official Name:
BRCA1-associated protein
NCBI Official Symbol:
BRAP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
Q7Z569
Protein GI Number:
296434410
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q7Z569
User NOte:
Optimal dilutions for each application to be determined by the researcher.