SIRPB1 Antibody
| Code | Size | Price |
|---|
| PSI-60-449-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD172b, SIRPB1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
signal-regulatory-protein (SIRP) family, and also belongs to the
immunoglobulin superfamily. SIRP family members are receptor-type
transmembrane glycoproteins known to be involved in the negative
regulation of receptor tyrosine kinase-coupled signaling processes.
This protein was found to interact with TYROBP/DAP12, a protein
bearing immunoreceptor tyrosine-based activation motifs. This
protein was also reported to participate in the recruitment of
tyrosine kinase SYK. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Background References:
- Gaikwad, S., et al. Am. J. Pathol. 175(6):2528-2539(2009)
- Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
- Martins-de-Souza, D., et al.Neural Transm 116(3):275-289(2009)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SIRPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-134 amino acids from the Central region of human SIRPB1.
NCBI Gene ID #:
10326
NCBI Official Name:
Signal-regulatory protein beta-1
NCBI Official Symbol:
SIRPB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
O00241
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O00241
User NOte:
Optimal dilutions for each application to be determined by the researcher.