MTMR14 Antibody
Code | Size | Price |
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PSI-59-225-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Myotubularin-related protein 14, 313-, HCV NS5A-transactivated protein 4 splice variant A-binding protein 1, NS5ATP4ABP1, hJumpy, MTMR14, C3orf29
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a myotubularin-related protein. The
encoded protein is a phosphoinositide phosphatase that specifically
dephosphorylates phosphatidylinositol 3,5-biphosphate and
phosphatidylinositol 3-phosphate. Mutations in this gene are
correlated with autosomal dominant centronuclear myopathy.
Alternate splicing results in multiple transcript variants. A
pseudogene of this gene is found on chromosome 18.
Background References:
- Gibbs, E.M., et al. Autophagy 6(6):819-820(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Vergne, I., et al. EMBO J. 28(15):2244-2258(2009)
- Tosch, V., et al. Hum. Mol. Genet. 15(21):3098-3106(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This MTMR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human MTMR14.
NCBI Gene ID #:
64419
NCBI Official Name:
Myotubularin-related protein 14
NCBI Official Symbol:
MTMR14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q8NCE2
Protein GI Number:
118568016
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8NCE2
User NOte:
Optimal dilutions for each application to be determined by the researcher.