ITK Antibody

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ProSci
Product Code: PSI-59-248
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-248-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).
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Western blot analysis in A549 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Tyrosine-protein kinase ITK/TSK, Interleukin-2-inducible T-cell kinase, IL-2-inducible T-cell kinase, Kinase EMT, T-cell-specific kinase, Tyrosine-protein kinase Lyk, ITK, EMT, LYK
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq].
Background References:
  • Grasis, J.A., et al. Mol. Cell. Biol. 30(14):3596-3609(2010)
  • Pechloff, K., et al. J. Exp. Med. 207(5):1031-1044(2010)
  • Qi, Q., et al. J. Biol. Chem. 284(43):29882-29892(2009)
  • Kogina, K., et al. Mol. Cells 28(2):125-130(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ITK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human ITK.
NCBI Gene ID #:
3702
NCBI Official Name:
Tyrosine-protein kinase ITK/TSK
NCBI Official Symbol:
ITK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q08881
Protein GI Number:
585361
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q08881
User NOte:
Optimal dilutions for each application to be determined by the researcher.