DEF6 Antibody
| Code | Size | Price |
|---|
| PSI-58-569-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Differentially expressed in FDCP 6 homolog, DEF-6, IRF4-binding protein, DEF6, IBP
Application Note:
For WB starting dilution is: 1:1000
Background:
DEF6, or IBP, is a guanine nucleotide exchange factor
(GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly
expressed in B and T cells (Gupta et al., 2003 [PubMed
12923183]).
Background References:
- Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
- Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
- Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
- Zhang, Z., et al. Cancer Epidemiol 33(2):130-136(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-528 amino acids from the C-terminal region of human DEF6.
NCBI Gene ID #:
50619
NCBI Official Name:
Differentially expressed in FDCP 6 homolog
NCBI Official Symbol:
DEF6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q9H4E7
Protein GI Number:
74761430
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9H4E7
User NOte:
Optimal dilutions for each application to be determined by the researcher.