PDLIM3 Antibody
| Code | Size | Price |
|---|
| PSI-60-169-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
PDZ and LIM domain protein 3, Actinin-associated LIM protein, Alpha-actinin-2-associated LIM protein, PDLIM3, ALP
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene contains a PDZ domain and
a LIM domain, indicating that it may be involved in cytoskeletal
assembly. In support of this, the encoded protein has been shown to
bind the spectrin-like repeats of alpha-actinin-2 and to colocalize
with alpha-actinin-2 at the Z lines of skeletal muscle. This gene
is found near a region of chromosome 4 that has been implicated in
facioscapulohumeral muscular dystrophy, but this gene does not
appear to be involved in the disease. Two transcript variants
encoding different isoforms have been found for this gene.
Background References:
- Hershberger, R.E., et al. Clin Transl Sci 1(1):21-26(2008)
- Keira, Y., et al. Neurosci. Res. 57(4):513-521(2007)
- Arola, A.M., et al. Mol. Genet. Metab. 90(4):435-440(2007)
- Klaavuniemi, T., et al. J. Biol. Chem. 279(25):26402-26410(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PDLIM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-355 amino acids from the C-terminal region of human PDLIM3.
NCBI Gene ID #:
27295
NCBI Official Name:
PDZ and LIM domain protein 3
NCBI Official Symbol:
PDLIM3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q53GG5
Protein GI Number:
74740479
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q53GG5
User NOte:
Optimal dilutions for each application to be determined by the researcher.