EDEM3 Antibody
| Code | Size | Price |
|---|
| PSI-58-568-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
ER degradation-enhancing alpha-mannosidase-like protein 3, Alpha-1,2-mannosidase EDEM3, EDEM3, C1orf22
Application Note:
For WB starting dilution is: 1:1000
Background:
Quality control in the endoplasmic reticulum (ER) ensures
that only properly folded proteins are retained in the cell through
recognition and degradation of misfolded or unassembled proteins.
EDEM3 belongs to a group of proteins that accelerate degradation of
misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed
16431915]).
Background References:
- Hirao, K., et al. J. Biol. Chem. 281(14):9650-9658(2006)
- Mast, S.W., et al. Glycobiology 15(4):421-436(2005)
- Olivari, S., et al. J. Biol. Chem. 280(4):2424-2428(2005)
- Sood, R., et al. Genomics 73(2):211-222(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EDEM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-802 amino acids from the C-terminal region of human EDEM3.
NCBI Gene ID #:
80267
NCBI Official Name:
ER degradation-enhancing alpha-mannosidase-like protein 3
NCBI Official Symbol:
EDEM3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
105 kDa
Protein Accession #:
Q9BZQ6
Protein GI Number:
166897965
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9BZQ6
User NOte:
Optimal dilutions for each application to be determined by the researcher.