ARL1 Antibody
Code | Size | Price |
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PSI-58-726-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
ADP-ribosylation factor-like protein 1, ARL1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the ARL
(ADP-ribosylation factor-like) family of proteins, which are
structurally related to ADP-ribosylation factors (ARFs). ARFs,
described as activators of cholera toxin (CT)
ADP-ribosyltransferase activity, regulate intracellular vesicular
membrane trafficking, and stimulate a phospholipase D (PLD)
isoform. Although, ARL proteins were initially thought not to
activate CT or PLD, later work showed that they are weak
stimulators of PLD and CT in a phospholipid dependent manner.
Background References:
- Houghton, F.J., et al. Cell 138(4):787-794(2009)
- Nishimoto-Morita, K., et al. J. Biol. Chem. 284(16):10583-10592(2009)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Zahn, C., et al. Mol. Membr. Biol. 23(6):475-485(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This ARL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human ARL1.
NCBI Gene ID #:
400
NCBI Official Name:
ADP-ribosylation factor-like protein 1
NCBI Official Symbol:
ARL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
P40616
Protein GI Number:
728888
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P40616
User NOte:
Optimal dilutions for each application to be determined by the researcher.