ACTL7B Antibody
| Code | Size | Price |
|---|
| PSI-58-536-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Actin-like protein 7B, Actin-like-7-beta, ACTL7B
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of a family
of actin-related proteins (ARPs) which share significant amino acid
sequence identity to conventional actins. Both actins and ARPs have
an actin fold, which is an ATP-binding cleft, as a common feature.
The ARPs are involved in diverse cellular processes, including
vesicular transport, spindle orientation, nuclear migration and
chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A,
are intronless, and are located approximately 4 kb apart in a
head-to-head orientation within the familial dysautonomia candidate
region on 9q31. Based on mutational analysis of the ACTL7B gene in
patients with this disorder, it was concluded that it is unlikely
to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A,
the ACTL7B gene is expressed predominantly in the testis, however,
its exact function is not known.
Background References:
- Humphray, S.J., et al. Nature 429(6990):369-374(2004)
- Hisano, M., et al. Nucleic Acids Res. 31(16):4797-4804(2003)
- Chadwick, B.P., et al. Genomics 58(3):302-309(1999)
- Schafer, D.A., et al. Annu. Rev. Cell Dev. Biol. 15, 341-363 (1999) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ACTL7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-97 amino acids from the N-terminal region of human ACTL7B.
NCBI Gene ID #:
10880
NCBI Official Name:
Actin-like protein 7B
NCBI Official Symbol:
ACTL7B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q9Y614
Protein GI Number:
27923724
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y614
User NOte:
Optimal dilutions for each application to be determined by the researcher.