ARHGEF18 Antibody
| Code | Size | Price |
|---|
| PSI-59-511-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Rho guanine nucleotide exchange factor 18, 114 kDa Rho-specific guanine nucleotide exchange factor, p114-Rho-GEF, p114RhoGEF, Septin-associated RhoGEF, SA-RhoGEF, ARHGEF18, KIAA0521
Application Note:
For WB starting dilution is: 1:1000
Background:
Rho GTPases are GTP binding proteins that regulate a wide
spectrum of cellular functions. These cellular processes include
cytoskeletal rearrangements, gene transcription, cell growth and
motility. Activation of Rho GTPases is under the direct control of
guanine nucleotide exchange factors (GEFs). The protein encoded by
this gene is a guanine nucleotide exchange factor and belongs to
the Rho GTPase GFE family. Family members share a common feature, a
Dbl (DH) homology domain followed by a pleckstrin (PH) homology
domain. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Background References:
- Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)
- Niu, J., et al. Circ. Res. 93(9):848-856(2003)
- Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :
- Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARHGEF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human ARHGEF18.
NCBI Gene ID #:
23370
NCBI Official Name:
Rho guanine nucleotide exchange factor 18
NCBI Official Symbol:
ARHGEF18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
131 kDa
Protein Accession #:
Q6ZSZ5
Protein GI Number:
296439444
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6ZSZ5
User NOte:
Optimal dilutions for each application to be determined by the researcher.