DVL2 Antibody
| Code | Size | Price |
|---|
| PSI-58-081-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the dishevelled (dsh)
protein family. The vertebrate dsh proteins have approximately 40%
amino acid sequence similarity with Drosophila dsh. This gene
encodes a 90-kD protein that undergoes posttranslational
phosphorylation to form a 95-kD cytoplasmic protein, which may play
a role in the signal transduction pathway mediated by multiple Wnt
proteins. The mechanisms of dishevelled function in Wnt signaling
are likely to be conserved among metazoans.
Background References:
- Inkster, B., et al. Neuroimage 53(3):908-917(2010)
- Kikuchi, K., et al. EMBO J. 29(20):3470-3483(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Gao, C., et al. Nat. Cell Biol. 12(8):781-790(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the C-terminal region of human DVL2.
NCBI Gene ID #:
1856
NCBI Official Name:
Segment polarity protein dishevelled homolog DVL-2
NCBI Official Symbol:
DVL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
O14641
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O14641
User NOte:
Optimal dilutions for each application to be determined by the researcher.