EFS Antibody

ProSci
Product Code: PSI-61-162
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-162-200ul200ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000-1:2000 dilution Lane 1: human fetal liver lysate Lane 2: human lung lysate Lane 3: Jurkat whole cell lysate Lane 4: K562 whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000-1:2000 dilution Lane 1: human fetal liver lysate Lane 2: human lung lysate Lane 3: Jurkat whole cell lysate Lane 4: K562 whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Embryonal Fyn-associated substrate, hEFS, Cas scaffolding protein family member 3, EFS, CASS3
Application Note:
For WB starting dilution is: 1:1000-1:2000
Background:
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity).
Background References:
  • Ishino M.,et al.Oncogene 15:1741-1745(1997).
  • Ota T.,et al.Nat. Genet. 36:40-45(2004).
  • Heilig R.,et al.Nature 421:601-607(2003).
  • Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EFS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 367-399 amino acids from the Central region of human EFS.
NCBI Gene ID #:
10278
NCBI Official Name:
Embryonal Fyn-associated substrate
NCBI Official Symbol:
EFS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
O43281
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O43281
User NOte:
Optimal dilutions for each application to be determined by the researcher.