MMS19 Antibody
| Code | Size | Price |
|---|
| PSI-60-132-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
MMS19 nucleotide excision repair protein homolog, hMMS19, MET18 homolog, MMS19-like protein, MMS19, MMS19L
Application Note:
For WB starting dilution is: 1:1000
Background:
MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types.
Background References:
- Ito, S., et al. Mol. Cell 39(4):632-640(2010)
- Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
- McWilliams, R.R., et al. Cancer Epidemiol. Biomarkers Prev. 18(4):1295-1302(2009)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-437 amino acids from the Central region of human MMS19.
NCBI Gene ID #:
64210
NCBI Official Name:
MMS19 nucleotide excision repair protein homolog
NCBI Official Symbol:
MMS19
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
113 kDa
Protein Accession #:
Q96T76
Protein GI Number:
150421597
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96T76
User NOte:
Optimal dilutions for each application to be determined by the researcher.