CORO2A Antibody
| Code | Size | Price |
|---|
| PSI-57-143-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Coronin-2A, IR10, WD repeat-containing protein 2, CORO2A, IR10, WDR2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the WD repeat protein
family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),
which may facilitate formation of heterotrimeric or multiprotein
complexes. Members of this family are involved in a variety of
cellular processes, including cell cycle progression, signal
transduction, apoptosis, and gene regulation. This protein contains
5 WD repeats, and has a structural similarity with actin-binding
proteins: the D. discoideum coronin and the human p57 protein,
suggesting that this protein may also be an actin-binding protein
that regulates cell motility. Alternative splicing of this gene
generates 2 transcript variants.
Background References:
- Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
- Marshall, T.W., et al. J. Cell. Sci. 122 (PT 17), 3061-3069 (2009) :
- Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
- Yoon, H.G., et al. Mol. Cell 12(3):723-734(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CORO2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human CORO2A.
NCBI Gene ID #:
7464
NCBI Official Name:
Coronin-2A
NCBI Official Symbol:
CORO2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
Q92828
Protein GI Number:
28381354
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q92828
User NOte:
Optimal dilutions for each application to be determined by the researcher.