NPNT Antibody

ProSci
Product Code: PSI-59-623
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-623-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Nephronectin, Preosteoblast EGF-like repeat protein with MAM domain, Protein EGFL6-like, NPNT, EGFL6L, POEM
Application Note:
For WB starting dilution is: 1:1000
Background:
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity).
Background References:
  • Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
  • Hancock, D.B., et al. Nat. Genet. 42(1):45-52(2010)
  • Kahai, S., et al. PLoS ONE(10), E7535 (2009) :
  • Huang, J.T., et al. Int. J. Mol. Med. 15(4):719-724(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NPNT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-392 amino acids from the Central region of human NPNT.
NCBI Gene ID #:
255743
NCBI Official Name:
Nephronectin
NCBI Official Symbol:
NPNT
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
Q6UXI9
Protein GI Number:
311033424
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6UXI9
User NOte:
Optimal dilutions for each application to be determined by the researcher.