MYOZ2 Antibody

ProSci
Product Code: PSI-59-197
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-197-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Myozenin-2, Calsarcin-1, FATZ-related protein 2, MYOZ2 (HGNC:1330)
Application Note:
For WB starting dilution is: 1:1000
Background:
MYOZ2 myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Background References:
  • Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
  • Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
  • Aurino, S., et al. Acta Myol 27, 90-97 (2008) :
  • Posch, M.G., et al. Med. Sci. Monit. 14 (7), CR372-CR374 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This MYOZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-71 amino acids from the N-terminal region of human MYOZ2.
NCBI Gene ID #:
51778
NCBI Official Name:
Myozenin-2
NCBI Official Symbol:
MYOZ2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
Q9NPC6
Protein GI Number:
74761638
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9NPC6
User NOte:
Optimal dilutions for each application to be determined by the researcher.