TJP2 Antibody
| Code | Size | Price |
|---|
| PSI-58-905-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tight junction protein ZO-2, Tight junction protein 2, Zona occludens protein 2, Zonula occludens protein 2, TJP2, X104, ZO2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a zonula occluden that is a member of
the membrane-associated guanylate kinase homolog family. The
encoded protein functions as a component of the tight junction
barrier in epithelial and endothelial cells and is necessary for
proper assembly of tight junctions. Mutation in this gene have been
identified in patients with hypercholanemia. Alternate splicing
results in multiple transcript variants.
Background References:
- Lechuga, S., et al. Exp. Cell Res. 316(19):3124-3139(2010)
- Remue, E., et al. FEBS Lett. 584(19):4175-4180(2010)
- Walsh, T., et al. Am. J. Hum. Genet. 87(1):101-109(2010)
- Meerschaert, K., et al. Cell. Mol. Life Sci. 66(24):3951-3966(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TJP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 981-1009 amino acids from the C-terminal region of human TJP2.
NCBI Gene ID #:
9414
NCBI Official Name:
Tight junction protein ZO-2
NCBI Official Symbol:
TJP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
134 kDa
Protein Accession #:
Q9UDY2
Protein GI Number:
317373313
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9UDY2
User NOte:
Optimal dilutions for each application to be determined by the researcher.