WIF1 Antibody
| Code | Size | Price |
|---|
| PSI-57-817-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Wnt inhibitory factor 1, WIF-1, WIF1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene functions to inhibit WNT
proteins, which are extracellular signaling molecules that play a
role in embryonic development. This protein contains a WNT
inhibitory factor (WIF) domain and five epidermal growth factor
(EGF)-like domains, and is thought to be involved in mesoderm
segmentation. This gene functions as a tumor suppressor gene, and
has been found to be epigenetically silenced in various cancers.
Background References:
- Licchesi, J.D., et al. Oncogene 29(44):5923-5934(2010)
- Fendri, A., et al. Cancer Invest. 28(9):896-903(2010)
- Kohno, H., et al. Oncol. Rep. 24(2):423-431(2010)
- Belshaw, N.J., et al. Carcinogenesis 31(6):1158-1163(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human WIF1.
NCBI Gene ID #:
11197
NCBI Official Name:
Wnt inhibitory factor 1
NCBI Official Symbol:
WIF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q9Y5W5
Protein GI Number:
61252765
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y5W5
User NOte:
Optimal dilutions for each application to be determined by the researcher.