Dok5 Antibody
| Code | Size | Price |
|---|
| PSI-56-408-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180
Application Note:
For WB starting dilution is: 1:1000
Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Background References:
- Liu, X., et al.Am Acad Child Adolesc Psychiatry 49(1):33-41(2010)
- Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010) :
- Shi, L., et al. Cell. Signal. 18(11):1995-2003(2006)
- Cai, D., et al. J. Biol. Chem. 278(28):25323-25330(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Dok5 antibody is generated from rabbits immunized with a recombinant protein (GST-tag removed) from human Dok5.
NCBI Gene ID #:
55816
NCBI Official Name:
Docking protein 5
NCBI Official Symbol:
DOK5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q9P104
Protein GI Number:
26393190
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q9P104
User NOte:
Optimal dilutions for each application to be determined by the researcher.