DOK5 Antibody
Code | Size | Price |
---|
PSI-58-990-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Images
Documents
Further Information
Additional Names:
Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the DOK
family of membrane proteins, which are adapter proteins involved in
signal transduction. The encoded protein interacts with
phosphorylated receptor tyrosine kinases to mediate neurite
outgrowth and activation of the MAP kinase pathway. In contrast to
other DOK family proteins, this protein does not interact with
RASGAP.
Background References:
- Liu, X., et al.Am Acad Child Adolesc Psychiatry 49(1):33-41(2010)
- Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010) :
- Shi, L., et al. Cell. Signal. 18(11):1995-2003(2006)
- Cai, D., et al. J. Biol. Chem. 278(28):25323-25330(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DOK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human DOK5.
NCBI Gene ID #:
55816
NCBI Official Name:
Docking protein 5
NCBI Official Symbol:
DOK5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q9P104
Protein GI Number:
26393190
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9P104
User NOte:
Optimal dilutions for each application to be determined by the researcher.