TLE4 Antibody
Code | Size | Price |
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PSI-56-757-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Transducin-like enhancer protein 4, Grg-4, Groucho-related protein 4, TLE4, GRG4, KIAA1261
Application Note:
For WB starting dilution is: 1:1000
Background:
TLE4 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Background References:
- Liu, Y., et al. PLoS Genet.(11), E1000707 (2009) :
- Hancock, D.B., et al. PLoS Genet.(8), E1000623 (2009) :
- Stolk, L., et al. Nat. Genet. (2009) In press :
- Dayyani, F., et al. Blood 111(8):4338-4347(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This TLE4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-196 amino acids from the N-terminal region of human TLE4.
NCBI Gene ID #:
7091
NCBI Official Name:
Transducin-like enhancer protein 4
NCBI Official Symbol:
TLE4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
Q04727
Protein GI Number:
158518541
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q04727
User NOte:
Optimal dilutions for each application to be determined by the researcher.