SNX27 Antibody
Code | Size | Price |
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PSI-64-201-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Sorting nexin-27, SNX27, KIAA0488
Application Note:
For WB starting dilution is: 1:1000
Background:
SNX27 encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein.
Background References:
- Lunn, M.L., et al. Nat. Neurosci. 10(10):1249-1259(2007)
- Nassirpour, R., et al. Channels (Austin) 1(5):331-333(2007)
- MacNeil, A.J., et al. Biochem. Biophys. Res. Commun. 359(4):848-853(2007)
- Rincon, E., et al. Mol. Cell Proteomics 6(6):1073-1087(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This SNX27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-340 amino acids from the Central region of human SNX27.
NCBI Gene ID #:
81609
NCBI Official Name:
Sorting nexin-27
NCBI Official Symbol:
SNX27
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Protein Accession #:
Q96L92
Protein GI Number:
166214988
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96L92
User NOte:
Optimal dilutions for each application to be determined by the researcher.