ARHGEF6 Antibody
| Code | Size | Price |
|---|
| PSI-58-685-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Rho guanine nucleotide exchange factor 6, Alpha-Pix, COOL-2, PAK-interacting exchange factor alpha, Rac/Cdc42 guanine nucleotide exchange factor 6, ARHGEF6, COOL2, KIAA0006, PIXA
Application Note:
For WB starting dilution is: 1:1000
Background:
Rho GTPases play a fundamental role in numerous cellular
processes that are initiated by extracellular stimuli that work
through G protein coupled receptors. The encoded protein belongs to
a family of cytoplasmic proteins that activate the Ras-like family
of Rho proteins by exchanging bound GDP for GTP. It may form a
complex with G proteins and stimulate Rho-dependent signals. This
protein is activated by PI3-kinase. Mutations in this gene can
cause X-chromosomal non-specific mental retardation. [provided by
RefSeq].
Background References:
- Maiti, A.K. Pharmacogenomics J. 10(2):94-104(2010)
- Eriguchi, M., et al. J. Neurol. Sci. 290 (1-2), 80-85 (2010) :
- Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
- Lim, J.W., et al. Scand. J. Gastroenterol. 44(10):1166-1172(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.
NCBI Gene ID #:
9459
NCBI Official Name:
Rho guanine nucleotide exchange factor 6
NCBI Official Symbol:
ARHGEF6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
87 kDa
Protein Accession #:
Q15052
Protein GI Number:
17371603
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q15052
User NOte:
Optimal dilutions for each application to be determined by the researcher.