PHEX Antibody
| Code | Size | Price |
|---|
| PSI-58-750-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Phosphate-regulating neutral endopeptidase, 3424-, Metalloendopeptidase homolog PEX, Vitamin D-resistant hypophosphatemic rickets protein, X-linked hypophosphatemia protein, HYP, PHEX, PEX
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a transmembrane
endopeptidase that belongs to the type II integral membrane
zinc-dependent endopeptidase family. The protein is thought to be
involved in bone and dentin mineralization and renal phosphate
reabsorption. Mutations in this gene cause X-linked
hypophosphatemic rickets.
Background References:
- Majewski, P.M., et al. J. Biol. Chem. 285(45):34828-34838(2010)
- Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
- Clausmeyer, S., et al. Calcif. Tissue Int. 85(3):211-220(2009)
- Gaucher, C., et al. Hum. Genet. 125(4):401-411(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PHEX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-595 amino acids from the C-terminal region of human PHEX.
NCBI Gene ID #:
5251
NCBI Official Name:
Phosphate-regulating neutral endopeptidase
NCBI Official Symbol:
PHEX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Protein Accession #:
P78562
Protein GI Number:
2499917
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P78562
User NOte:
Optimal dilutions for each application to be determined by the researcher.