COL10A1 Antibody

ProSci
Product Code: PSI-60-517
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-517-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Collagen alpha-1(X) chain, COL10A1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).
Background References:
  • Makitie, O., et al. J. Orthop. Res. 28(11):1497-1501(2010)
  • Wang, S., et al. Connect. Tissue Res. 51(3):188-196(2010)
  • Videman, T., et al. Arthritis Rheum. 60(2):470-481(2009)
  • Higashikawa, A., et al. Arthritis Rheum. 60(1):166-178(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.
NCBI Gene ID #:
1300
NCBI Official Name:
Collagen alpha-1(X) chain
NCBI Official Symbol:
COL10A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
66 kDa
Protein Accession #:
Q03692
Protein GI Number:
2506306
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q03692
User NOte:
Optimal dilutions for each application to be determined by the researcher.