GH2 Antibody
| Code | Size | Price |
|---|
| PSI-58-499-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Growth hormone variant, GH-V, Growth hormone 2, Placenta-specific growth hormone, GH2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
somatotropin/prolactin family of hormones which play an important
role in growth control. The gene, along with four other related
genes, is located at the growth hormone locus on chromosome 17
where they are interspersed in the same transcriptional
orientation; an arrangement which is thought to have evolved by a
series of gene duplications. The five genes share a remarkably high
degree of sequence identity. Alternative splicing generates
additional isoforms of each of the five growth hormones, leading to
further diversity and potential for specialization. As in the case
of its pituitary counterpart, growth hormone 1, the predominant
isoform of this particular family member shows similar somatogenic
activity, with reduced lactogenic activity. Mutations in this gene
lead to placental growth hormone/lactogen deficiency. [provided by
RefSeq].
Background References:
- McElholm, A.R., et al. Gastroenterology 139(1):204-212(2010)
- de Jesus Romero-Prado, M.M., et al. Gene 452(1):7-15(2010)
- Christiansen, M. Prenat. Diagn. 29(13):1249-1255(2009)
- Zeck, W., et al. Pediatr. Res. 63(4):353-357(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human GH2.
NCBI Gene ID #:
2689
NCBI Official Name:
Growth hormone variant
NCBI Official Symbol:
GH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P01242
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P01242
User NOte:
Optimal dilutions for each application to be determined by the researcher.