SGCA Antibody
| Code | Size | Price |
|---|
| PSI-59-032-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin, Dystroglycan-2, SGCA, ADL, DAG2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a component of the
dystrophin-glycoprotein complex (DGC), which is critical to the
stability of muscle fiber membranes and to the linking of the actin
cytoskeleton to the extracellular matrix. Its expression is thought
to be restricted to striated muscle. Mutations in this gene result
in type 2D autosomal recessive limb-girdle muscular dystrophy.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Mendell, J.R., et al. Ann. Neurol. 68(5):629-638(2010)
- Fernandez, K., et al. Am. J. Pathol. 176(1):416-434(2010)
- Klinge, L., et al. Neuromuscul. Disord. 18(12):934-941(2008)
- Delgado-Olguin, P., et al. Biochim. Biophys. Acta 1779(1):74-80(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SGCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-266 amino acids from the Central region of human SGCA.
NCBI Gene ID #:
6442
NCBI Official Name:
Alpha-sarcoglycan
NCBI Official Symbol:
SGCA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q16586
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q16586
User NOte:
Optimal dilutions for each application to be determined by the researcher.