AMTN Antibody

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ProSci
Product Code: PSI-59-502
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-502-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in T47D cell line lysates (35ug/lane).
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Western blot analysis in T47D cell line lysates (35ug/lane).

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Further Information

Additional Names:
Amelotin, AMTN
Application Note:
For WB starting dilution is: 1:1000
Background:
The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).
Background References:
  • Moffatt, P., et al. Biochem. J. 399(1):37-46(2006)
  • Iwasaki, K., et al. J. Dent. Res. 84(12):1127-1132(2005)
  • Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004)
  • Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AMTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human AMTN.
NCBI Gene ID #:
401138
NCBI Official Name:
Amelotin
NCBI Official Symbol:
AMTN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q6UX39
Protein GI Number:
55976710
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6UX39
User NOte:
Optimal dilutions for each application to be determined by the researcher.