PKD2L1 Antibody

ProSci
Product Code: PSI-58-469
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-469-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
Polycystic kidney disease 2-like 1 protein, Polycystin-2 homolog, Polycystin-2L1, Polycystin-L, Polycystin-L1, PKD2L1, PKD2L, PKDL, TRPP3
Application Note:
For WB starting dilution is: 1:1000
Background:
PKD2L1 is a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.
Background References:
  • Molland, K.L., et al. Biochem. J. 429(1):171-183(2010)
  • Kawaguchi, H., et al. J. Biol. Chem. 285(23):17277-17281(2010)
  • Li, Q., et al. J. Neurochem. 103(6):2391-2400(2007)
  • Geng, L., et al. J. Cell. Sci. 119 (PT 7), 1383-1395 (2006) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PKD2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human PKD2L1.
NCBI Gene ID #:
9033
NCBI Official Name:
Polycystic kidney disease 2-like 1 protein
NCBI Official Symbol:
PKD2L1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Protein Accession #:
Q9P0L9
Protein GI Number:
23821938
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9P0L9
User NOte:
Optimal dilutions for each application to be determined by the researcher.