VPS4B Antibody
| Code | Size | Price |
|---|
| PSI-57-287-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the AAA
protein family (ATPases associated with diverse cellular
activities), and is the homolog of the yeast Vps4 protein. In
humans, two paralogs of the yeast protein have been identified. The
former share a high degree of aa sequence similarity with each
other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1
(suppressor of K+ transport defect 1) has been shown to be a yeast
Vps4 ortholog. Functional studies indicate that both human paralogs
associate with the endosomal compartments, and are involved in
intracellular protein trafficking, similar to Vps4 protein in
yeast. The gene encoding this paralog has been mapped to chromosome
18; the gene for the other resides on chromosome 16. [provided by
RefSeq].
Background References:
- Morita, E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(29):12889-12894(2010)
- McDonough, C.W., et al. Hum. Genet. (2009) In press :
- Bruce, E.A., et al. Virology 390(2):268-278(2009)
- Inoue, M., et al. Traffic 9(12):2180-2189(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This VPS4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-332 amino acids from the C-terminal region of human VPS4B.
NCBI Gene ID #:
9525
NCBI Official Name:
Vacuolar protein sorting-associated protein 4B
NCBI Official Symbol:
VPS4B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
O75351
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O75351
User NOte:
Optimal dilutions for each application to be determined by the researcher.