ILKAP Antibody
| Code | Size | Price |
|---|
| PSI-60-521-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Integrin-linked kinase-associated serine/threonine phosphatase 2C, ILKAP, ILKAP
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a protein
serine/threonine phosphatase of the PP2C family. This protein can
interact with integrin-linked kinase (ILK/ILK1), a regulator of
integrin mediated signaling, and regulate the kinase activity of
ILK. Through the interaction with ILK, this protein may selectively
affect the signaling process of ILK-mediated glycogen synthase
kinase 3 beta (GSK3beta), and thus participate in Wnt signaling
pathway.
Background References:
- Nakrieko, K.A., et al. Cell Cycle 7(14):2157-2166(2008)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.
NCBI Gene ID #:
80895
NCBI Official Name:
Integrin-linked kinase-associated serine/threonine phosphatase 2C
NCBI Official Symbol:
ILKAP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q9H0C8
Protein GI Number:
74752560
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9H0C8
User NOte:
Optimal dilutions for each application to be determined by the researcher.