SNX1 Antibody

ProSci
Product Code: PSI-57-439
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-439-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysates from Hela, 293T cell line (from left to right), using SNX1 Antibody at 1:1000 at each lane.

Western blot analysis of lysates from Hela, 293T cell line (from left to right), using SNX1 Antibody at 1:1000 at each lane.

Further Information

Additional Names:
Sorting nexin-1, SNX1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.
Background References:
  • Nisar, S., et al. Traffic 11(4):508-519(2010)
  • Mari, M., et al. Traffic 9(3):380-393(2008)
  • Bryant, D.M., et al. J. Cell. Sci. 120 (PT 10), 1818-1828 (2007) :
  • Rojas, R., et al. Mol. Cell. Biol. 27(3):1112-1124(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This SNX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the C-terminal region of human SNX1.
NCBI Gene ID #:
6642
NCBI Official Name:
Sorting nexin-1
NCBI Official Symbol:
SNX1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q13596
Protein GI Number:
17380569
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q13596
User NOte:
Optimal dilutions for each application to be determined by the researcher.