SIRPB2 Antibody
| Code | Size | Price |
|---|
| PSI-60-379-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Signal-regulatory protein beta-2, SIRP-beta-2, Protein tyrosine phosphatase non-receptor type substrate 1-like 3, Protein tyrosine phosphatase non-receptor type substrate protein, SIRPB2, PTPN1L, PTPNS1L3
Application Note:
For WB starting dilution is: 1:1000
Background:
Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
Background References:
- Nyati, M.K., et al. Cancer Res. 66(24):11554-11559(2006)
- van den Berg, T.K., et al. J. Immunol. 175(12):7788-7789(2005)
- Chen, J., et al. Proc. Natl. Acad. Sci. U.S.A. 99(19):12257-12262(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SIRPB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-255 amino acids from the C-terminal region of human SIRPB2.
NCBI Gene ID #:
284759
NCBI Official Name:
Signal-regulatory protein beta-2
NCBI Official Symbol:
SIRPB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
Q5JXA9
Protein GI Number:
74762205
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q5JXA9
User NOte:
Optimal dilutions for each application to be determined by the researcher.