RAB27A Antibody

ProSci
Product Code: PSI-60-957
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-957-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from K562 cell line, using RAB27A Antibody at 1:1000.

Western blot analysis of lysate from K562 cell line, using RAB27A Antibody at 1:1000.

Further Information

Additional Names:
Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Background References:
  • Ohbayashi, N., et al. Pigment Cell Melanoma Res 23(3):365-374(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Meeths, M., et al. Pediatr Blood Cancer 54(4):563-572(2010)
  • Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Immunogen:
This RAB27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human RAB27A.
NCBI Gene ID #:
5873
NCBI Official Name:
Ras-related protein Rab-27A
NCBI Official Symbol:
RAB27A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
P51159
Protein GI Number:
116242744
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P51159
User NOte:
Optimal dilutions for each application to be determined by the researcher.