SEC23IP Antibody
Code | Size | Price |
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PSI-57-779-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
SEC23-interacting protein, p125, SEC23IP
Application Note:
For WB starting dilution is: 1:1000
Background:
COPII-coated vesicles are involved in protein transport
from the endoplasmic reticulum to the Golgi apparatus. The protein
encoded by this gene was identified by its interaction with a mouse
protein similar to yeast Sec23p, an essential component of the
COPII. This protein shares significant similarity with
phospholipid-modifying proteins, especially phosphatidic acid
preferring-phospholipase A1. Overexpression of this protein has
been shown to cause disorganization of the endoplasmic
reticulum-Golgi intermediate compartment and Golgi apparatus, which
suggests its role in the early secretory pathway. [provided by
RefSeq].
Background References:
- Ong, Y.S., et al. J. Cell Biol. 190(3):331-345(2010)
- Trynka, G., et al. Gut 58(8):1078-1083(2009)
- Li, H., et al. J. Biol. Chem. 281(21):14748-14755(2006)
- Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SEC23IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 724-752 amino acids from the C-terminal region of human SEC23IP.
NCBI Gene ID #:
11196
NCBI Official Name:
SEC23-interacting protein
NCBI Official Symbol:
SEC23IP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
111 kDa
Protein Accession #:
Q9Y6Y8
Protein GI Number:
55584014
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y6Y8
User NOte:
Optimal dilutions for each application to be determined by the researcher.