PPIE Antibody
| Code | Size | Price |
|---|
| PSI-59-279-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Peptidyl-prolyl cis-trans isomerase E, PPIase E, Cyclophilin E, Cyclophilin-33, Rotamase E, PPIE, CYP33
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases
catalyze the cis-trans isomerization of proline imidic peptide
bonds in oligopeptides and accelerate the folding of proteins. This
protein contains a highly conserved cyclophilin (CYP) domain as
well as an RNA-binding domain. It was shown to possess PPIase and
protein folding activities, and it also exhibits RNA-binding
activity. Alternative splicing results in multiple transcript
variants. A related pseudogene, which is also located on chromosome
1, has been identified.
Background References:
- Park, S., et al. Biochemistry 49(31):6576-6586(2010)
- Hom, R.A., et al. J. Mol. Biol. 400(2):145-154(2010)
- Wang, Z., et al. Cell 141(7):1183-1194(2010)
- Naukkarinen, J., et al. PLoS Genet.(6), E1000976 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This PPIE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of human PPIE.
NCBI Gene ID #:
10450
NCBI Official Name:
Peptidyl-prolyl cis-trans isomerase E
NCBI Official Symbol:
PPIE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q9UNP9
Protein GI Number:
13124097
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9UNP9
User NOte:
Optimal dilutions for each application to be determined by the researcher.