CLK1 Antibody
| Code | Size | Price |
|---|
| PSI-62-968-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dual specificity protein kinase CLK1, CDC-like kinase 1, CLK1, CLK
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection.
Background References:
- Prasad, J., et al., Mol. Cell. Biol. 23(12):4139-4149 (2003). Talmadge, C.B., et al., Hum. Genet. 103(4):523-524 (1998). Hanes, J., et al., J. Mol. Biol. 244(5):665-672 (1994). Johnson, K.W., et al., J. Biol. Chem. 266(6):3402-3407 (1991). Ben-David, Y., et al., EMBO J. 10(2):317-325 (1991).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human CLK1.
NCBI Gene ID #:
1195
NCBI Official Name:
Dual specificity protein kinase CLK1
NCBI Official Symbol:
CLK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
P49759
Protein GI Number:
206729857
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
P49759
User NOte:
Optimal dilutions for each application to be determined by the researcher.