PPME1 Antibody

ProSci
Product Code: PSI-59-093
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-093-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis of PPME1 using rabbit polyclonal PPME1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPME1 gene.

Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis of PPME1 using rabbit polyclonal PPME1 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PPME1 gene.

Further Information

Additional Names:
Protein phosphatase methylesterase 1, PME-1, PPME1, PME1
Application Note:
For WB starting dilution is: 1:1000
Background:
Protein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit (PPP2CA; MIM 176915) (Ogris et al., 1999 [PubMed 10318862]).
Background References:
  • Puustinen, P., et al. Cancer Res. 69(7):2870-2877(2009)
  • Longin, S., et al. Exp. Cell Res. 314(1):68-81(2008)
  • Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
  • Ogris, E., et al. J. Biol. Chem. 274(20):14382-14391(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This PPME1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 351-379 amino acids from the C-terminal region of human PPME1.
NCBI Gene ID #:
51400
NCBI Official Name:
Protein phosphatase methylesterase 1
NCBI Official Symbol:
PPME1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q9Y570
Protein GI Number:
47606055
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y570
User NOte:
Optimal dilutions for each application to be determined by the researcher.