VPS45 Antibody

ProSci
Product Code: PSI-58-263
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-263-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse brain tissue lysates (35ug/lane).

Western blot analysis in mouse brain tissue lysates (35ug/lane).

Further Information

Additional Names:
Vacuolar protein sorting-associated protein 45, h-VPS45, hlVps45, VPS45, VPS45A, VPS45B
Application Note:
For WB starting dilution is: 1:1000
Background:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. [provided by RefSeq].
Background References:
  • Rahajeng, J., et al. Exp. Cell Res. 316(5):859-874(2010)
  • Kim, B.Y., et al. Biochem. Biophys. Res. Commun. 311(3):577-582(2003)
  • Dulubova, I., et al. EMBO J. 21(14):3620-3631(2002)
  • de Renzis, S., et al. Nat. Cell Biol. 4(2):124-133(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This VPS45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 461-489 amino acids from the C-terminal region of human VPS45.
NCBI Gene ID #:
11311
NCBI Official Name:
Vacuolar protein sorting-associated protein 45
NCBI Official Symbol:
VPS45
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q9NRW7
Protein GI Number:
23396937
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9NRW7
User NOte:
Optimal dilutions for each application to be determined by the researcher.