TNIP2 Antibody

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ProSci
Product Code: PSI-58-630
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-630-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

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Further Information

Additional Names:
TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein, TNIP2 {ECO:0000312|EMBL:EAW825141}
Application Note:
For WB starting dilution is: 1:1000
Background:
TNIP2 binds to the C-terminal zinc finger domain of A20 (TNFAIP3; MIM 191163) and is involved in activation of the ERK (see MAPK3; MIM 601795) MAP kinase pathway in various cell types (Van Huffel et al., 2001 [PubMed 11390377]; Papoutsopoulou et al., 2006 [PubMed 16633345]).
Background References:
  • Raychaudhuri, S., et al. Nat. Genet. 41(12):1313-1318(2009)
  • Handoyo, H., et al. Biochem. J. 424(1):109-118(2009)
  • Verstrepen, L., et al. Biochem. Pharmacol. 78(2):105-114(2009)
  • Huang, L., et al. Oncogene 27(47):6131-6140(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the Central region of human TNIP2.
NCBI Gene ID #:
79155
NCBI Official Name:
TNFAIP3-interacting protein 2
NCBI Official Symbol:
TNIP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
Q8NFZ5
Protein GI Number:
74715616
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8NFZ5
User NOte:
Optimal dilutions for each application to be determined by the researcher.